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KMID : 1147820140030020111
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Journal of Naturopathy
2014 Volume.3 No. 2 p.111 ~ p.118
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Analyses of Amino acid Concentrations in the Decoctions of Gagam Nanganjeon Herbs
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Lee Seok-Ha
Lee Chae-Yun
Lee Seong-Guk
Lee Hyung-Hoan
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Abstract
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This study was designed to analyze, using the HPLC method, the quantity and types of amino acids found in the Gagam nanganjeon herbs decoction prescribed to women for treatment of infertility. Eighteen types of L-amino acids were discovered in the 100 g of Gagam Nanganjeon decoction. There were 50 mg of pro, 40 mg of ser, 38.5 mg of arg, 19.6 mg of ala, 14.5 mg of asp and the rest were 13 types of L-amino acid ranging from 0.33~6.2 mg. In the 100 g of Lycium fruit decoction, there were 12 types of amino acids. The quantity of arg was highest with 28 mg, and the rest ranged from 0.125~1.3 mg. Angelica root decoction contained 18 types of amino acids: arg was the most abundant with 71 mg, and the rest ranged from 0.16~5.6 mg. Poria decoction contained 7 types of amino acids: asp was most abundant at 0.5 mg, and the rest ranged from 0.1~0.2 mg. Lindera root decoction contained 14 types of amino acids: ser was most abundant with 6.9 mg, and the rest ranged from 0.14~6.64 mg. Fennel decoction contained 14 types amino acids. Arg was the most abundant at 4.2 mg, and the rest ranged from 0.3~3.2 mg. Cinnamon decoction contained 4 types of amino acids ranging from 0.08~0.37 mg. Costus root decoction contained 15 types of amino acids and it contained especially large amounts of pro at 36 mg, and 0.12~7.8 mg of other amino acids. Evodia decoction contained 14 types of amino acids: large quantity of pro at 11.2 mg, and the rest ranged from 0.19~6.2 mg. Ginger decoction contained 17 types of amino acids: large quantities of ala at 11.2 mg, ser at 10.4 mg, and the rest ranged from 0.06~2.6 mg. Prepared aconite decoction contained small quantities of 4 amino acids. Ginseng decoction contained 12 types of amino acids: large quantities of arg at 27.9% and the rest ranged from 0.12~1.3 mg. In conclusion, we found that each herb in the formula of Gagam nangajnjeon, when combined, contributed 18 amino acids, which assisted in protein and enzyme synthesis necessary for pregnancy. This finding supports the claim that decocting individual herbs do not create the same desired effect as combining herbs in an herbal formula. The particular combination of herbs and the way they react with each other is an important part of understanding the efficacy of this particular prescription.
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KEYWORD
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Infertility, Gagam Nanganjeon, Amino acid, Lycium, Ginseng, Arginine, Serine
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